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2-(2-phenoxybenzylidene)-1-(2,4-dinitrophenyl)hydrazine (15d)


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(4-NITRO-PHENYL)-THIAZOL-2-YL]-HYDRAZINE;4-(4-nitrophenyl)-2 ..

Hydrazine Hydrochloride 4-Nitrophenyl Hydrazine Hydrochloride 2-Nitrophenyl Hydrazine Hydrochloride 4-Bromo Phenyl Hydrazine Hydrochloride 4-Methyl Phenyl Hydrazine Hydrochloride ...


2-phenoxybenzoic acid hydrazide 8 which used in the preparation of compounds 10b-10e was synthesized according to our previously described method () (). Target compounds were synthesized in one step shown in and . The designed compounds 10a-10e and 15a-15d were synthesized by acid-catalyzed condensation of hydrazides 7 and 8 or hydrazines 11-14 with corresponding aldehydes 9a-9d. The structures of the synthesized compounds were assigned on the basis of IR, 1H-NMR and Mass spectra.

(2-methoxy-4-nitrophenyl)hydrazine CAS#: 41978-94-3

The uses of non-steroidal anti-inflammatory drugs (NSAIDs) are limited by a variety of side effects. So research on preparing new analgesic agents is important. According to some reports about the analgesic activity of hydrazide and hydrazine derivatives a new series of these compounds were synthesized in order to obtain new analgesic compounds. The final compounds 10a-10e and 15a-15d were prepared by condensation of corresponding hydrazides 7,8 and 11-14 with different aldehydes 9a-9e. The structures of all synthesized compounds were confirmed by means of FT-IR, 1H-NMR and Mass spectra. All compounds were evaluated for their analgesic activities by abdominal constriction test (writhing test). Most of the synthesized compounds induced significant reduction in the writhing response when compared to control and compound 15 was more potent than mefenamic acid in the writhing test.

(2-Nitrophenyl)hydrazine || cas 3034-19-3 || …

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