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TKA Aseptic Loosening - Recon - Orthobullets

THA Aseptic Loosening - Recon - Orthobullets

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aseptic loosening of hip prosthesis

The most common situations that lead to the need for a revision hip replacement are instability / dislocation, mechanical loosening and infection. According to one national review study, instability issues account for 22% of all revision hip replacements, aseptic loosening for 20% and infection the cause of 15% of yearly revision hip replacement surgeries [3]. Periprosthetic fracture, component failure and osteolysis-related wear are the causes for the remaining revision hip replacements done each year. Of great concern looking forward is that infection by the year 2030 will account for 48% of all revision hip replacements that will be done [4]. This has grave economic implications as infection is one of the most expensive complicating events related to joint replacement surgery.

ASEPTIC LOOSENING OF TOTAL HIP REPLACEMENT | …

Despite a variety of high technology, proving a joint to be infected remains one of the most challenging and elusive diagnoses and is an area of constant research to improve this discovery process. Some low virulent organisms can defy preoperative discovery only to present in florid fashion once a revision joint has been re-implanted for what was thought to be aseptic mechanical loosening; a very disappointing situation for a patient to face and harder yet to prove that the infection was present all along.

Aseptic Loosening in Uncemented Total Hip …

Aseptic loosening is a major cause of failure of total hip arthroplasty

Tsukayama et al. proposed a 4-stage system consisting of early postoperative-, late chronic-, and acute hematogenous infections, and positive intraoperative cultures of specimens obtained during revision of a presumed aseptically loose total hip prosthesis [].


The outcome of hip arthroplasty in the acromegalic population is poorly documented. We report a case of aseptic loosening of an uncemented cup in an acromegalic patient. The alteration of GH-levels can alter osseointegration process through various biological mechanisms.

Distinguishing infection from aseptic loosening is ..

Aseptic Loosening in Uncemented Total Hip Arthroplasty in a Canine Model

Revision hip replacement refers to the procedure to repair or replace a failed first hip replacement. Over the past three decades total hip replacement has become one of the most important surgical procedures to return patients to active, contributing members of society. The surgical procedure to replace a worn out, painful hip with prosthetic components () has been performed on millions of patients with great results and overall few complications. Once reserved for the senior citizen with a sedentary lifestyle, total hip replacement is rapidly becoming an operation in demand by a mid-life, still working patient population who demand high function and long lasting mechanical properties to coincide with a highly active lifestyle.

METHODS: In 7 Dutch hospitals, 176 consecutive patients with the preoperative diagnosis of aseptic loosening of their total hip arthroplasty were enrolled.

aseptic loosening from infection can be ..
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of aseptic loosening of an uncemented total hip ..

A specific radiological evaluation of hip joint infections does not exist to our knowledge. However, several authors have used different radiological systems that have been primarily developed for determining acetabular and femoral defects at the site of an aseptic loosening of hip arthroplasties also in the assessment of infected total hip replacements. The Paprosky- [, ], and the AAOS (American Academy of Orthopedic Surgeons) [-] classifications belong to the most widely used ones.

and aseptic loosening around the prosthesis

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8. Isaac GH, Brockett C, Breckon A, van der Jagt D, Williams S, Hardaker C, et al. Ceramic-on-metal bearings in total hip replacement: whole blood metal ion levels and analysis of retrieved components. J Bone Joint Surg Br 2009;91(9):1134-1141.
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and in most cases aseptic loosening ..

Since each failed hip replacement has a different reason for its failure, preparing for the revision hip replacement is also going to be unique. Specialized CAT scans or MRI tests may be needed to evaluate bone loss around the current implant or position of the prosthesis relative to the normal anatomy. Various laboratory or nuclear scans to check for infection may be indicated such as CBC, CRP, Sed. Rate or Bone Scan. An aspiration of the hip joint may yield fluid that can be analyzed by cell count and culture. Finally, consultations with other medical or surgical specialists may be required to evaluate the medical condition or special circumstances of the patient prior to surgery to optimize the outcome.

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