Call us toll-free

Synthetic Biodegradable Polymers - Google Books

outlining the synthesis, biodegradability and biomedical applications of biodegradable synthetic and natural polymers

Approximate price

Pages:

275 Words

$19,50

Precision Synthesis of Biodegradable Polymers | …

Examples of synthetic biodegradable chemistries discussed in this handbook include polycaprolactones, polyesters, phosphazenes, phosphoesters, and polyanhydrides.

Synthesis and processing of biodegradable and bio-based polymers by microwave ..

Polymers that display a physicochemical response to stimuli are widely explored as potential drug-delivery systems. Stimuli studied to date include chemical substances and changes in temperature, pH and electric field. Homo polymers or copolymers of N-isopropylacrylamide and poly(ethylene oxide)- poly(propylene oxide)-poly(ethylene oxide) (known as poloxamers) are typical examples of thermosensitive polymers, but their use in drug delivery is problematic because they are toxic and nonbiodegradable. Biodegradable polymers used for drug delivery to date have mostly been in the form of injectable microspheres or implant systems, which require complicated fabrication processes using organic solvents. Such systems have the disadvantage that the use of organic solvents can cause denaturation when protein drugs are to be encapsulated. Furthermore, the solid form requires surgical insertion, which often results in tissue irritation and damage. Here we report the synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid). Aqueous solutions of these copolymers exhibit temperature-dependent reversible gel- sol transitions. The hydrogel can be loaded with bioactive molecules in an aqueous phase at an elevated temperature (around 45 °C), where they form a sol. In this form, the polymer is injectable. On subcutaneous injection and subsequent rapid cooling to body temperature, the loaded copolymer forms a gel that can act as a sustained-release matrix for drugs.

Fatty acid-based biodegradable polymers: Synthesis …

Assisted Solvent-Free or Aqueous-Based Synthesis of Biodegradable Polymers.

This review summarizes the main advances published over the last 15 years, outlining the synthesis, biodegradability and biomedical applications of biodegradable synthetic and natural polymers.">

This review summarizes the main advances published over the last 15 years, outlining the synthesis, biodegradability and biomedical applications of biodegradable synthetic and natural polymers.

Nanocomposites with Biodegradable Polymers: Synthesis, ..

Nanocomposites with biodegradable polymers : synthesis, properties and future perspectives

AB - Polymers that display a physicochemical response to stimuli are widely explored as potential drug-delivery systems. Stimuli studied to date include chemical substances and changes in temperature, pH and electric field. Homo polymers or copolymers of N-isopropylacrylamide and poly(ethylene oxide)- poly(propylene oxide)-poly(ethylene oxide) (known as poloxamers) are typical examples of thermosensitive polymers, but their use in drug delivery is problematic because they are toxic and nonbiodegradable. Biodegradable polymers used for drug delivery to date have mostly been in the form of injectable microspheres or implant systems, which require complicated fabrication processes using organic solvents. Such systems have the disadvantage that the use of organic solvents can cause denaturation when protein drugs are to be encapsulated. Furthermore, the solid form requires surgical insertion, which often results in tissue irritation and damage. Here we report the synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid). Aqueous solutions of these copolymers exhibit temperature-dependent reversible gel- sol transitions. The hydrogel can be loaded with bioactive molecules in an aqueous phase at an elevated temperature (around 45 °C), where they form a sol. In this form, the polymer is injectable. On subcutaneous injection and subsequent rapid cooling to body temperature, the loaded copolymer forms a gel that can act as a sustained-release matrix for drugs.

N2 - Polymers that display a physicochemical response to stimuli are widely explored as potential drug-delivery systems. Stimuli studied to date include chemical substances and changes in temperature, pH and electric field. Homo polymers or copolymers of N-isopropylacrylamide and poly(ethylene oxide)- poly(propylene oxide)-poly(ethylene oxide) (known as poloxamers) are typical examples of thermosensitive polymers, but their use in drug delivery is problematic because they are toxic and nonbiodegradable. Biodegradable polymers used for drug delivery to date have mostly been in the form of injectable microspheres or implant systems, which require complicated fabrication processes using organic solvents. Such systems have the disadvantage that the use of organic solvents can cause denaturation when protein drugs are to be encapsulated. Furthermore, the solid form requires surgical insertion, which often results in tissue irritation and damage. Here we report the synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid). Aqueous solutions of these copolymers exhibit temperature-dependent reversible gel- sol transitions. The hydrogel can be loaded with bioactive molecules in an aqueous phase at an elevated temperature (around 45 °C), where they form a sol. In this form, the polymer is injectable. On subcutaneous injection and subsequent rapid cooling to body temperature, the loaded copolymer forms a gel that can act as a sustained-release matrix for drugs.

Order now
  • Biodegradable AB Diblock Copolymers

    Polymers

  • Sigma-Aldrich Online Catalog Product List: PEG-PCL

    Synthesis and NMR characterization of aliphatic …

  • Title: Biodegradable Plastics 1 Biodegradable Plastics

    Biopolymer - Wikipedia

Order now

Nanocomposites: synthesis, structure, properties and …

The majority of biobased or biodegradable polyesters are completely aliphatic. They usually have a low melting point and glass transition temperature and poor hydrolytic stability, that is, they are rather hydrophilic and, therefore, will have a moderate to high water uptake when exposed to moisture. This will effect the mechanical properties and stability. For this reason, some biodegradable polymers have been blended with more stable polymers or have been copolymerized with aromatic building blocks (aromatic acids or anhydrides). For example, poly(butylene adipate-co-terephthalate) (PBAT) is commercially synthesized from adipic acid, terephthalic acid, and 1,4-butane diol.

AQA | Chemistry | Subject content | Organic chemistry

Important synthetic biodegradable polyesters are (PESu), poly(propylene succinate) (PPSu) and (PBSu) among several others. They are typically produced from the reaction of a diacid or acid anhydride with a diol with the elimination of water. Most aliphatic polyesters are currently produced from fossil fuels. However, some of these polyesters can also be produced using monomers from renewable resources. Many succinates have been intensively studied due to their inherent biodegradability and commercial availability. PPSu has gained an increasing interest because its biodegradation rate is higher than those of most other succinates like poly(ethylene succinate) (PESu) and poly(butylene succinate) (PBSu). Due to its low crystallinity, it also degrades faster than most other polyesters used as pharmaceutical excipients including polycaprolactone (PCL).

Synthetic Polymers Application Notes - Wyatt …

The use of silver nanoparticles (AgNPs) is gaining in popularity due to silver’s antibacterial properties. Conventional methods for AgNP synthesis require dangerous chemicals and large quantities of energy (heat) and can result in formation of hazardous byproducts. This article summarizes recent activity in this general area where environmentally friendly synthetic techniques are currently being explored for the synthesis of “greener” AgNPs including the use of plant extracts, biodegradable polymers, and enzymes/bacteria and alternative energy input systems, such as microwave irradiation. Microwave heating enables efficient formation of nanostructures of uniform small sizes in shorter reaction times with reduced energy consumption; preventing agglomeration of ensuing nanoparticles is an additional attribute.

Order now
  • Kim

    "I have always been impressed by the quick turnaround and your thoroughness. Easily the most professional essay writing service on the web."

  • Paul

    "Your assistance and the first class service is much appreciated. My essay reads so well and without your help I'm sure I would have been marked down again on grammar and syntax."

  • Ellen

    "Thanks again for your excellent work with my assignments. No doubts you're true experts at what you do and very approachable."

  • Joyce

    "Very professional, cheap and friendly service. Thanks for writing two important essays for me, I wouldn't have written it myself because of the tight deadline."

  • Albert

    "Thanks for your cautious eye, attention to detail and overall superb service. Thanks to you, now I am confident that I can submit my term paper on time."

  • Mary

    "Thank you for the GREAT work you have done. Just wanted to tell that I'm very happy with my essay and will get back with more assignments soon."

Ready to tackle your homework?

Place an order