From Gene to Protein—Transcription and Translation
Protein Expression and Sorting
RAD51C IN DNA FORK PROTECTION AND STABILITY
Prerequisite: or Electrical generation, transmission, and distribution systems with an emphasis on 3 phase analysis, design, short circuit currents due to symmetrical faults, and reliability considerations of the electric power system. The laboratory portion includes hands on activities and experiments that align electric power theory with application. Design considerations for inside / outside plant, worker safety, system interconnection and protection, while focusing on reliability and cost considerations are covered.
Prerequisites: A Grade of C or higher in ( or ) and .This course is an introduction to the field of biomaterials with an emphasis on the wound healing process and interactions between the human body and implanted devices fabricated from various types of biomaterials. The thrust of this course will be to illuminate the processes occurring at the tissue-biomaterial interface. Attention will be given to the biological events occurring at the molecular level on the surface of an implanted device. The nature of these surfaces and the physiological consequences of these processes will be examined in terms of how the body and functioning of the device are impacted.
TARGETING RAD52 PROTEIN-PROTEIN INTERACTIONS IN CANCER THERAPY
Express yourself through your genes! See if you can generate and collect three types of protein, then move on to explore the factors that affect protein synthesis in a cell.
Walter Chazin (Vanderbilt University)
'UNDERSTANDING HOW DNA PRIMASE WORKS REQUIRES KNOWLEDGE OF ITS ARCHITECTURAL DYNAMICS'
Karlene Cimprich (Stanford University School of Medicine)
'MECHANISMS FOR MAINTAINING GENOME STABILITY AT THE REPLICATION FORK'
David Cortez (Vanderbilt University)
'FUNCTIONS OF SINGLE-STRAND DNA BINDING PROTEINS IN MAINTAINING GENOME STABILITY'
Sheila David (University of California, Davis)
'BASE EXCISION REPAIR GLYCOSYLASES MUTYH AND NEIL1: THE GOOD, THE BAD AND THE DAMAGED'
Michelle Debatisse (Gustave Roussy Institute)
'COMMON FRAGILE SITE INSTABILITY: A RACE AGAINST TIME'
Sylvie Doublié (University of Vermont)
'STRUCTURAL ANALYSES OF DNA POLYMERASE THETA VARIANTS'
PROTEOMICS-GRADE STRATEGIES FOR INTEGRATIVE STRUCTURAL BIOLOGY
Structural analyses of DNA polymerase theta variants'
Brandt Eichman (Vanderbilt University)
'MECHANISMS OF REMODELING STALLED REPLICATION FORKS'
Dorothy Erie (University of North Carolina)
Ilya Finkelstein (University of Texas at Austin)
'ASSEMBLING THE HUMAN RESECTOSOME ONE MOLECULE AT A TIME'
Marco Foiani (University of Milan)
'AN INTEGRATED ATR, ATM AND mTOR-MECHANICAL NETWORK CONTROLLING NUCLEAR PLASTICITY AND CELL MIGRATIONB'
Mark Glover (University of Alberta)
'PNKP - A MEANS TO FIX THE ENDS'
Jane Grasby (Krebs Institute)
'COUPLING RECOGNITION AND REACTIVITY IN A STRUCTURE-SPECIFIC NUCLEASE'
Samir Hamdan (KAUST)
'SINGLE MOLECULE VIEW OF THE STRUCTURE SPECIFIC 5' NUCLEASES'
Reuben Harris (University of Minnesota)
'APOBEC MUTAGENESIS IN CANCER'
Karl-Peter Hopfner (Ludwig-Maximilians-University Munich)
'STRUCTURAL ANALYSIS OF PROTEIN DNA REMODELLER'
Ben Van Houten (University of Pittsburgh)
'DAMAGE SENSOR ROLE OF UV-DDB DURING BASE EXCISION REPAIR:STIMULATION OF APE1 AND OGG1'
The 3rd DNA Replication/Repair Structures & Cancer conference in February 2018 will focus on structural and mechanistic insights into dynamic protein, chromatin, DNA and RNA complexes acting in DNA replication and repair events relevant to cancer. Conference talks and discussions will center on developing an actionable mechanistic knowledge of DNA replication and repair stress responses suitable to guide advanced intervention strategies for cancer. The conference will emphasize an environment suitable for initiating productive collaborations. It will include vibrant informal and formal discussions together with informative talks and poster sessions.
STRUCTURAL ANALYSIS OF PROTEIN DNA REMODELLER
Protein Synthesis (transcription ..
IDENTIFICATION OF UHRF2 (RNF107) AS A NOVEL ICL SENSOR PROTEIN REQUIRED FOR THE FANCONI ANEMIA PATHWAY
Biology Animations: protein synthesis animation
THE CONCERTED ROLES OF FANCM AND Rad52 IN THE PROTECTION OF COMMON FRAGILE SITES
A collection of Protein Synthesis ..
-hydrogen bonding between water molecules-protein organization -protein folding ..
(short animations of biological processes) Water/Buffers. Proteins
Meindert Lamers (Leiden University Medical Center)
'STRUCTURAL FEATURES OF HIGH FIDELITY DNA REPLICATION'
Susan Lees-Miller (Arnie Charbonneau Cancer Institute)
'NON-REPAIR FUNCTIONS OF DNA-PKcs'
Karolin Luger (University of Colorado at Boulder)
'POLY (ADP-RIBOSE) POLYMERASE 1 IN DNA DAMAGE RECOGNITION'
Mauro Modesti (Cancer Research Center of Marseille)
'DYNAMICS AND MECHANICS OF DNA TETHERING BY CORE c-NHEJ FACTORS AND BY THE MRE11/RAD50/NBS1 COMPLEX'
Zachary Nagel (Harvard University)
'COMPREHENSIVE ANALYSIS OF DNA REPAIR CAPACITY IN NORMAL AND CANCEROUS CELLS'
Mark O'Connor (AstraZeneca)
'TARGETING THE REPLICATION STRESS RESPONSE IN CANCER'
John Pascal (Université de Montréal)
'STRUCTURAL BIOLOGY OF POLY(ADP-ribose) POLYMERASE ENZYMES'
Tanya Paull (University of Texas at Austin)
'THE Mre11-Rad50-Nbs1 COMPLEX AND REGULATION OF DNA REPAIR'
Phoebe Rice (University of Chicago)
'AN MCM-RELATED HELICASE AND OTHER REPLICATION-RELATED MACHINERY FOUND ON THE MOBILE ELEMENT BEHIND THE MRSA EPIDEMIC'
Andrej Sali (University of California, San Francisco)
'INTEGRATIVE STRUCTURE MODELING OF DNA-PKcs'
Orlando Scharer (Ulsan National Institute of Science and Technology)
'REPLICATIVE AND TRANSLESION SYNTHESIS DNA POLYMERASES IN ICL REPAIR'
Katharina Schlacher (MD Anderson Cancer Center)
'RAD51C IN DNA FORK PROTECTION AND STABILITY'
David Schriemer (University of Calgary)
'PROTEOMICS-GRADE STRATEGIES FOR INTEGRATIVE STRUCTURAL BIOLOGY'
Titia Sixma (NKI)
'STRUCTURAL BIOLOGY OF DNA MISMATCH REPAIR'
Maria Spies (University of Iowa)
'INHIBITORS OF THE RAD52-ssDNA INTERACTION'
Terence Strick (Institut Jacques Monod)
'SINGLE-MOLECULE ANALYSIS OF MULTICOMPONENT DNA REPAIR SYSTEMS'
Madalena Tarsounas (The CR-UK/MRC Oxford Institute for Radiation Oncology)
'WNT/b-CATENIN SIGNALING IN BRCA-DEFICIENT CELLS'
DNA and protein synthesis AQA B2 by zuba102 - …
Prerequisite: , and ( or ) all with a C or better. This laboratory course is designed to provide students with valuable hands-on experience in the field of cellular and biomaterial engineering. Experiments include biomaterial fabrication and characterization, mechanical testing of biomaterials, colorimetric protein assay, cell-based assay, the basics of cell culture techniques, the basics of light and electron microscopy, and image capture and analysis. A lecture on the principles of a given technique will be followed by laboratory activity.
DNA and Protein Synthesis - BioTopics Website
Prerequisite: , ( or ), , and . This course is an introduction to the field of tissue engineering as a therapeutic approach to treating damaged or diseased tissues in the biotechnology industry. In essence, new and functional living tissue can be fabricated by delivering cells, scaffolds, DNA, proteins, and/or protein fragments at surgery. This course will cover the advances in the fields of cell biology, molecular biology, material science and their relationship towards developing novel "tissue engineered" therapies.
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