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A Green Synthesis of Camphor 8

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The bioreduction mechanism of the aqueous plant leaf extract ..

The importance of catechols as efficient anchoring groups has been highlighted in recent excellent reviews partly dedicated to the characterization of their adhesive mechanisms onto surfaces and to their applications.

Green Synthesis of Metallic Nanoparticles via ..

Natural organic acids (NOAs) were efficient as green catalysts for the eco-friendly synthesis of xanthenones (up to 93% of yield) via one-pot reaction and under solvent-free conditions. Theoretical calculations to evaluate this reaction mechanism and regioselectivity as well as the potential anti-calcium blockers properties of xanthenones were described for the first time. Details are presented in the Article Natural Organic Acid as Green Catalyst for Xanthenones Synthesis: Methodology, Mechanism and Calcium Channel Blocking Activity by on page 2313.

Paclitaxel is one of several cytoskeletal drugs that target tubulin

A Green Synthesis of Camphor

, (pronounced /ˈkæmfə/) is a waxy, white or transparent solid with a strong, aromatic odor. It is a terpenoid with the chemical formula It is found in wood of the camphor laurel (), a large evergreen tree found in Asia (particularly in Sumatra, Borneo and Taiwan) and also of Dryobalanops aromatica, a giant of the Bornean forests. It also occurs in some other related trees in the laurel family, notably Ocotea usambarensis. Dried rosemary leaves (Rosmarinus officinalis), in the mint family, contain up to 20% camphor. It can also be synthetically produced from oil of turpentine. It is used for its scent, as an ingredient in cooking (mainly in India), as an embalming fluid, for medicinal purposes, and in religious ceremonies. A major source of camphor in Asia is camphor basil.
Norcamphor is a camphor derivative with the three methyl groups replaced by hydrogen.

Transient receptor potential vanilloid-3 () is a thermo-sensitive ion channel expressed in
skin keratinocytes and in a variety of neural cells. is a member of thermo-TRPs, and a
structural homologue of transient receptor potential vanilloid-1 (TRPV1). It is heat-sensitive but capsaicin-insensitive. It is activated by warmth as well as monoterpenoids including camphor, menthol, dihydrocarveol and 1,8-cineol. Recently, it has been proposed that voltage, temperature and chemical cues act through independent mechanisms.
is predominantly expressed in human keratinocytes. In humans it is co-expressed with in skin, tongue, dorsal root ganglion, trigeminal ganglion, spinal cord and brain. is implicated in skin sensitization and hyperalgesia in inflamed tissues and shows increased expression in the case of peripheral nerve injury.
Camphor is known to produce a warm sensation (Green, 1990), consistent with the thermal activation range of However, repeated camphor applications sensitized apparently contradicting its analgesic role
In fact prolonged exposure (5-15 minutes) of monoterpenoids results in agonist-specific desensitization of
It was observed Ca2+independent desensitization of channels during prolonged incubation with camphor, 1,8-cineol, mentol.
While the bicyclic monoterpenoids (camphor or 1,8-cineol) induce both acute desensitization and tachyphylaxis,
monocyclic monoterpenoids (dihydrocarveol or menthol) preferentially induce only tachyphylaxis.

Defining chemical reactions of the polyphenol class

Frontiers Antimicrobial Activity and Mechanism of Inhibition of Silver Nanoparticles against Extreme Halophilic Archaea Microbio

"Naessens's theories about the underlying causes and mechanisms of cancer are clearly not consistent with current scientific opinion. Although a small number of researchers have long believed that certain bacteria, viruses and other organisms such as cell-wall deficient or pleomorphic bacteria play a much more important role in the development of cancer, this view is not generally accepted by mainstream scientists." (Kaegi)

2. An increase in the specific immune responses principally assured by lymphocytes (B and T) and macrophages which acting together detect cells and foreign bodies, germs and cancerous cells flowing through the body. These immune responses are triggered to establish contact with foreign substances, destroy them and then eliminate them so that they will not impede the normal metabolic functions of the body's organs. 714X thus allows a weakened organism the opportunity to regain its defense mechanisms and therefore enhance the process of cellular repair.

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  • R 36/38 - Irritating to skin and eyes

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    Paclitaxel - Wikipedia

  • Synthesis of Camphor by the Oxidation of Borneol | …

    Polyphenol - Wikipedia

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synthesis of camphor by retro-synthesis

The present review considers the working mechanisms of antimicrobial polymers and of contact-active antimicrobial surfaces based on examples of recent research as well as on multifunctional antimicrobial materials.

Green synthesis of palladium nanoparticles using broth …

714X is not toxic and does not destroy diseased cells. It only supports the body's natural defense mechanisms and its immune system. It can be used with conventional treatments whether they be chemotherapy, surgery, radiation therapy or other therapies. It does not hinder their respective modes of action nor does it modify their effectiveness. 714X combined with conventional therapies can only benefit the patient as it promotes the elimination of metabolic waste matter (meaning toxins) produced by the above mentioned conventional treatments. It can also reduce the intensity of certain side effects associated with conventional therapies such as nausea, loss of appetite, etc. as it helps the body to cleanse itself by favoring the circulation of the lymph and by assisting in cellular repair by bringing nitrogen to the organism.

A New Camphor Synthesis - Journal of the American …

In this Review, an overview of different antimicrobial polymers, their mechanism of action, factors affecting antimicrobial activity, and application in various fields are given.

X. Jones Reaction: The Oxidation of Borneol to Camphor

However, if one considers cancer as a generalized disease which localizes itself in a vulnerable area of the body, it becomes useless to act locally if the defense mechanisms are not supported. In this approach, the tumor is only confirmation of a more profound problem.

Side reactions in oxidation of borneol to camphor? | …

isolated yomogin, a sesquiterpene lactone, which exhibited a novel histamine H1 receptor antagonism in the ileum. The presence of competitive histamine receptor antagonist and smooth muscle relaxant effects on the ileum and trachea explains its traditional use in asthma and the hyperactive gut.
and Staphylococcus aureus. Results showed the leaf plant extracts to possess antimicrobial activity against various test organisms used (E. coli, Staph aureus). The aqueous and alcohol extracts were more effective than traditional antibiotics used.
. Results showed inhibition of parasitaemia. Antinociceptive activity was also seen in the hot plate test indication a central, supra-spinally mediated mechanism for relieving pain. Results showed oral activity, non-toxicity, and a weed with a potential for a cheap source of plant-based antimalarial.
Results showed aqueous, chloroform and ethyl acetate extracts showed significant antimicrobial activity when compared to standard.

ated aqueous extracts of Artemisia vulgaris, Cichorium intybus, Smilax glabra, Solanum nigrum and Swertia chirayta against various human cancer cell lines. Results showed A. vulgaris exerted an inhibitory effect on cell growth and colony formation of prostate, breast, and colorectal cells.
ated an alcoholic extract of aerial parts of A. vulgaris on estrous cycle and implantation in female albino rats. Results suggest an antifertility effect with induction of irregular estrous cycle and increase in number of metestrus phase, 80% anti-implantation activity. There was no observed toxicity at high dose of 3000 mg/k p.o.
ated an aqueous root extract of A. vulgaris for hypolipidemic activity in cholesterol diet induced hyperlipidemic rats. Results showed significant serum lipid lowering effects with decrease in TC, TG, LDL, VLDL, with increased level of HDL and atherogenic index (AI). The hypolipidemic activity was comparable to rosuvastatin.
ated the larvicidal activity of methanol extracts of roots, stem and leaves of A. vulgaris against 3rd and 4th instars larvae of Culex quinquefasciatus. Leaves extract showed significantly higher mortality compared to root and stem extracts. Results suggest a potential for the methanol extract of leaves for mosquito control.

Stems analyzed for essential oil yielded major components viz., camphor, camphene, α-thujone, 1,8-cineole, γ-muurolene and β-caryophyllene. Mosquito larvicidal assay against 3rd instar larvae of Aedes aegypti showed 100% larval mortality with 500 ppm oil solution exposed for 8 hours. Results suggest a potential source of natural insecticides.
Study evaluated the toxicity of Artemisa vulgaris extracted oil from buds (AVO-b) and leaves (AVO-l) against human HL-60 promyelocytic leukemia and other cancer cell lines. Results showed EO-induced apoptosis in HL-60 cell mediated by caspase dependent pathways. AVO-b and AVO-l are more efficient in inducing apoptosis in different cancer cell lines rather than noncancerous cells.
Study showed leaves of A. vulgaris can inhibit growth of rats. The effect was attributed to blockade in energy generation process and interference in pentose pathway for production of NADPH and pentose sugar for synthesis of nucleic acid. The study sends a message for restricted use of leaves in treatment of various ailments.

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