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L., The Convergence of Synthetic Organic and Polymer Chemistries.

In this core unit, you will learn all about the reactions and mechanisms – the core of organic chemistry.

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Organic Chemistry Practice Problems at Michigan State University

V.; Van der Eycken, E., A microwave-assisted click chemistry synthesis of 1,4-disubstituted 1,2,3-triazoles via a copper(I)-catalyzed three-component reaction.

Organic Chemistry Portal - Reactions

Organic chemistry students typically struggle with the retrosynthetic approach to solving synthesis problems because most textbooks present the chemistry grouped by "reactions of the functional group". In contrast, the retrosynthetic approach requires the student to envision "reactions that yield the functional group". A second challenge is the inability to visualize the bond-forming and bond-breaking events that allow for predictive chemistry on the basis of reaction mechanism. Here we describe an original, easily implemented approach toward simultaneously addressing both problems. Starting in the middle of the first semester of organic chemistry—where reactions are typically first introduced—students begin to construct a "functional group transformation" notebook, or FGT. As reactions are presented in class, the students log these reactions, including the mechanism, in a reverse context, or a reactions that yield context. By the middle of the second semester of organic chemistry, where the retrosynthetic approach is addressed in full, the students have a notebook organized by functional group formed. The students are, in an ongoing sense, learning to think about organic reactions in both the forward and the reverse (retrosynthetic) sense from the middle of the first semester of organic chemistry through the end of the second semester while also recopying all the mechanistic details associated with each reaction.

25th International Symposium: Synthesis in Organic Chemistry

J., Efficient microwave-assisted synthesis of multivalent dendrimeric peptides using cycloaddition reaction (click) chemistry.

For access to the full system content, please get in touch with your local Wiley representative or sign up through as they are currently the exclusive distributor of Reaction Explorer for higher-education organic chemistry courses.

Organic chemistry is mostly about one element - carbon. The diversity in its valence and connectivity leads to millions of organic compounds and thousands of organic reactions. It is overwhelming if you adapt a brute force and rote memorization approach. Focus on the foundamentals such as electronic structures, nomenclatures, stereochemistry, reactions and mechanisms, the learning will flow. These are the exact skills you will learn from this series.

Modern Organic Synthesis - An Introduction - Organic chemistry

H.; Kluger, C., Azide/alkyne-

The favorite online resource (of our tutors) for organic chem is the Virtual Textbook of Organic Chemistry by Dr. Reusch at MSU.
It is VERY in-depth, but it also includes a TON of practice problems.

F., III, Towards organo-click chemistry: Development of organocatalytic multicomponent reactions through combinations of Aldol, Wittig, Knoevenagel, Michael, Diels-Alder and Huisgen cycloaddition reactions.

R., DNA-templated organic synthesis: Nature's strategy for controlling chemical reactivity applied to synthetic molecules.
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