Call us toll-free

Levocetirizine Impurities | Levocetirizine Related …

Synthesis of vortioxetine via (2-(piperazine-1-yl)phenyl)aniline intermediates - Patent 2894154

Approximate price

Pages:

275 Words

$19,50

Synthesis of N -Heterocycles - Organic Chemistry Portal

We believe that our phenyl-piperazine-triazine-based α-helix mimetics, along with the facile and divergent solid-phase synthetic method, have great potential as powerful tools for discovering potent inhibitors of given α-helix-mediated PPIs.

CHEMICALS & REAGENTS of UNITED QUANTUM …

Sushil et al (2011) synthesize 2-[4-(aryl substituted) piperazin-1-yl]-N-phenylacetamides and evaluate for the anti psychotic activity. All the 10 new arylpipeazines showed variable antipsychotic activity with compound 3h being the least effective in the induction of catalepsy. Their effect may involve interaction with 5-HT2A and D2 receptors. 33

PDF Downloads : Oriental Journal of Chemistry

Jacek sapa et al (2011 synthesized a series of novel pyrrolidin-2-one derivatives (17 compounds) with adrenolytic properties were evaluated for antiarrhythmic, electrocardiographic and antioxidant activity. Some of them displayed antiarrhythmic activity in barium chloride-induced arrhythmia and in the rat coronary artery ligation-reperfusion model, and slightly decreased the heart rate, prolonged P–Q, Q–T intervals and QRS complex. Among them, compound EP-40 (1-[2-hydroxy-3-[4-[(2-hydroxyphenyl) piperazin-1-yl] propyl] pyrrolidin-2-one showed excellent antiarrhythmic activity

Alka Bali et al (2010) synthesized a series of acetophenone based 1-(Aryloxy propyl) -4-(chloro aryl) piperazine. All the synthesized compounds were evaluated for anti psychotic activity. All the targeted compounds were subjected to preliminary pharmacological evaluation to determine their ability to antagonize Apomorphine induced mesh climbing behavior and apomorphine induced stereotype in mice. Compound a1-4 and b1 and b2 shows positive result for reversal of Apomorphine induced mesh climbing and compound a5-8 shows negative response. Apomorphine used as a standard drug.

Soai Tetrahedron Lett., 1981, 2859-2862

Biological testing of these compounds proved that these have the anticonvulsant and antidepressant activities. Mutlu Dilsiz aytmir et al (2010) also reported the synthesis and evaluation of anticonvulsant activity of 3-hydroxy-6-methyl-2-substituted 4H pyran-4-one derivatives. Among the compounds 4-(3-trifluoromethyl phenyl) piperazine -1-yl methyl group at position 2 on the pyranone ring. 26

Rangappa et al. (2006) worked on the 1-[bis(4-flurophenyl)methyl]piperazine derivatives(Fig.17) synthesis and there efficacy for acetylcholinestrase inhibition as a stimulant of central cholinergic neurotramission in Alzheimer’s disease.

Order now
  • Molbank, an international, peer-reviewed Open Access journal.

    Design, Solid-Phase Synthesis, and Evaluation of a Phenyl-Piperazine-Triazine Scaffold as α-Helix Mimetics

  • synthesis of 2, 6-methylated piperazine

    Recent Literature

  • Design, synthesis and pharmacological evaluation of N …

    Heterocyclic Building Blocks

Order now
  • Kim

    "I have always been impressed by the quick turnaround and your thoroughness. Easily the most professional essay writing service on the web."

  • Paul

    "Your assistance and the first class service is much appreciated. My essay reads so well and without your help I'm sure I would have been marked down again on grammar and syntax."

  • Ellen

    "Thanks again for your excellent work with my assignments. No doubts you're true experts at what you do and very approachable."

  • Joyce

    "Very professional, cheap and friendly service. Thanks for writing two important essays for me, I wouldn't have written it myself because of the tight deadline."

  • Albert

    "Thanks for your cautious eye, attention to detail and overall superb service. Thanks to you, now I am confident that I can submit my term paper on time."

  • Mary

    "Thank you for the GREAT work you have done. Just wanted to tell that I'm very happy with my essay and will get back with more assignments soon."

Ready to tackle your homework?

Place an order