Synthesis of the macrocyclic core of sanglifehrin a
The synthesis of the C 1 N 12 tripeptide of the novel immunosuppressant sanglifehrin A is described
Synthesis of the C29-C39 fragment of sanglifehrin A - …
“Synthesis of Macrolide Analogues of Sanglifehrin by RCM : Unique Reactivity of a Ruthenium Carbene Complex Bearing an Imidazol-2-ylidene Ligand.” 65.26 (2000): 9255–9260.
Lorenz).Polyene Cyclization to Adociasulfate 1 (Thomas Lindel and Cordula Hopmann).Sanglifehrin A: An Immunosuppressant Natural Product from Malawi (Thomas Lindel).Short Syntheses of the Spirotryprostatins (Thomas Lindel).The Chemical Total Synthesis of Proteins (Oliver Seitz).Solid-Phase Synthesis of Oligosaccharides (Ulf Diederichsen and Thomas Wagner).Polymer-Supported Synthesis of Non-Oligomeric Natural Products (Stefan Sommer, et al.).Explosions as a Synthetic Tool?
Total Synthesis of the Immunosuppressant Sanglifehrin A, K.C
(2013) TOTAL SYNTHESIS OF (+)-ASPICILIN, (+)-BOURGEANIC ACID, STEREOSELECTIVE SYNTHESIS OF C13-C26 FRAGMENT OF 53-DEOXO-SANGLIFEHRIN A AND DEVELOPMENT OF NEW METHODOLOGIES. PhD thesis, Indian Institute of Chemical Technology, Hyderabad.
Recent examples include the total synthesis of TaxolTM, brevetoxins A and B, epothilones A and B, eleutherobin and sarcodictyins, vancomycin, CP molecules, sanglifehrin A, everninomicin, a number of bisorbicillinoids, apoptolidin and diazonamide A.
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“Synthesis of Macrolide Analogues of Sanglifehrin by RCM : Unique Reactivity of a Ruthenium Carbene Complex Bearing an Imidazol-2-ylidene Ligand.” 65 (26): 9255–9260.
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Cell death is regulated by a variety of mechanisms
Further elaboration led to the synthesis of the C13 C19 segment of sanglifehrin A. Graphic. Download full-size image;
Immunosuppressive Drugs for Kidney Transplantation …
What are PPIases
Macrocyclics and Constrained Peptides Conference
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