Most pet foods contain 4-D ingredients.
4-Methylimidazole and Related Compounds
Short-term studies Mice In a 4- to 6-week study, albino Swiss mice (10 males and 10 females/group) were fed caramel colour III containing 830 ppm 4-methylimidazole at concentrations of 0, 1, 2, 4, 8, or 16% in the diet.
4,4′-(1-Methylethylidene)bisphenol, polymer with (chloromethyl)oxirane, and 2(dimethylamino)ethanol-blocked polyalkylenepolyphenylene isocyanate, lactates (salts)
Phenylimidazole 2-Ethylimidazole 2-Ethyl-4 ...
Phenol, 4,4′-(1-methylethylidene)bis-, polymer with (chloromethyl)heteromonocycle, 1,3-propanediamine, 2-methyl-N,N-dimethyl-1,5-pentanediamine, neodecanoic acid, hetermonocyclicmethyl ester, capped with 2,2′-iminobisethanol, salt with 2-hydroxypropanoic acid
The reaction product of dihydro-undecyl-heteromonocycleethanamine, with oxirane, mono[(C12-14-alkyloxy)methyl] derivs. and 2-hydroxypropanoic acid
36-2 ] 2-Ethyl-4-methylimidazole 其它名称： 2E4MZ ...
2,5-Cyclohexadiene-1,4-dione, 2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-, (all-E)-
1,6-Hexanediamine, N,N′-bis(2,2,6,6-tetramethyl-4-piperidinyl)-, polymers with morpholine-2,4,6-trichloro-1,3,5-triazine reaction products, methylated
Toxicity of caramel color products.
Subchronic toxicity study of ammonia caramel color type AC2 in rats.
N,N'-Carbonyl Diimidazole|N-Methylimidazole|2-Ethyl-4-methylimidazole|2-Ethylimidazole|2,2-Dimethyethanamine ...
90-day toxicity study of caramel color (ammonia process) in rats.
1-phenyl-4-methylimidazole Inh 4 – 1-(p-tolyl)-4-methylimidazole Table I.
New and higher yielding synthetic routes to -protected -methylpyrrole and -methylimidazole amino acids are introduced to circumvent difficulties associated with established schemes. Key steps in each synthesis include copper-mediated cross-coupling reaction to directly install a carbamate-protected 4-amine in the -methylpyrrole derivative and effective nitration followed by a one-pot reduction/Boc protection of the amine in the synthesis of the -Me-imidazole amino acid.
1H-2,1,3-Benzothiadiazin-4(3H)-one, 3-(1-methylethyl)-, 2,2-dioxide
The sixteenth meeting reviewed further information on the composition of caramel colours produced by the ammonia process, including the 4-methylimidazole content.
In the present study, the formation of 4(5)-methylimidazole in Maillard reaction model ...
Subacute oral toxicity of caramel coloring (coded Sample A) - dogs.
In January 2015, a public commitment was made by Environment Canada and Health Canada to review all orders and notices that were adopted between 2001 and 2014 to impose SNAc requirements. The purpose of the review is to ensure that SNAc orders and notices are consistent with current information, policies and approaches. Resulting changes to SNAc orders and notices are expected to provide greater clarity of scope and improved ease of compliance by industry, while protecting Canadians and their environment. This NOI reflects the results of the review of the SNAc Notice on the substance Clarified oils (petroleum), catalytic cracked, reaction products with cresol and polymethylene polyphenylene isocyanate identified by stakeholders as a priority.
Oxirane, 2-ethyl-, polymer with oxirane, mono-C12-14-sec-alkyl ethers
CARAMEL COLOUR III EXPLANATION In earlier evaluations, the presence of 4-methylimidazole in caramel colour III was noted, particularly since this compound was likely to be the causal agent of convulsions in cattle and sheep fed ammonia-treated molasses.
However, at its twenty-first meeting, the Committee (Annex 1, reference 44) no longer considered this a cause for concern since the introduction of chemical specifications limits the concentration of 4-methylimidazole in caramel colour III.
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