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Synthesis of norfloxacin analogues catalyzed by Lewis …

Tetracyclines are protein synthesis inhibitors primary targeting the 30S ribosome. They are essentially bacteriostatic.

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One-Pot Synthesis of Norfloxacin Ethyl Ester from 3 …

Aminoglycosides are rapidly bactericidal antibiotics which inhibit protein synthesis. These agents mainly interfere with proofreading process. Aminoglycosides are the only bactericidal class among protein synthesis inhibitors.

Synthesis of pyochelin-norfloxacin conjugates - …

A novel drug agent named norfloxacin biomonomer was developed in order to solve the problem of low drug content, uneven drug distribution, low molecular weight, and wide molecular weight distribution of polymer drug, based on polyurethane, which was used as an antibacterial agent to control the bacterial infection associated with biofilm formation on polymeric materials used in biologic environments. In this research, norfloxacin biomonomer was synthesized by esterifying the compound of norfloxacin. High-performance liquid chromatography system was used to analyze the purity of the final product and intermediate products, and Fourier transform infrared spectrometer and mass spectrum were used to verify the final product and intermediate products. The results showed that the objective product was developed successfully. The final product of norfloxacin biomonomer could be incorporated into the polyurethane as chain extender.

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T1 - Synthesis and study of norfloxacin labeled with technecium-99m as a potential imaging agent of bacterial inflammations

AB - Investigations have been carried out into creation of reagent for 99mTc-labeled norfloxacin hydrochloride (NFH). The NFH synthesized in the Institute of Organic Synthesis (Ekaterinburg, Russia) was used in this research. The effect of the mixture components on the radiochemical specimen purity was assessed using the method of thin-layer chromatography. The inflammation animal model was used to demonstrate the NFH functional eligibility for diagnostics of inflammatory processes.

N2 - Investigations have been carried out into creation of reagent for 99mTc-labeled norfloxacin hydrochloride (NFH). The NFH synthesized in the Institute of Organic Synthesis (Ekaterinburg, Russia) was used in this research. The effect of the mixture components on the radiochemical specimen purity was assessed using the method of thin-layer chromatography. The inflammation animal model was used to demonstrate the NFH functional eligibility for diagnostics of inflammatory processes.

Synthesis and characterization of norfloxacin …

Synthesis, crystal structure, and characterization of three novel compounds of the quinolone family member (norfloxacin).

Investigations have been carried out into creation of reagent for 99mTc-labeled norfloxacin hydrochloride (NFH). The NFH synthesized in the Institute of Organic Synthesis (Ekaterinburg, Russia) was used in this research. The effect of the mixture components on the radiochemical specimen purity was assessed using the method of thin-layer chromatography. The inflammation animal model was used to demonstrate the NFH functional eligibility for diagnostics of inflammatory processes.

Synthesis and characterization of norfloxacin-transition metal complexes (group 11, IB): spectroscopic, thermal, kinetic measurements and biological activity.

Synthesis, characterization and antibacterial activity of novel Fe(III), Co(II), and Zn(II) complexes with norfloxacin.
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  • Synthesis of norfloxacin analogues ..

    Norfloxacin is a synthetic antibacterial agent that belongs to the class of fluoroquinolone antibiotics

  • Synthesis of Norfloxacin Artificial Antigen

    Synthesis and biological evaluation of a mutual prodrug of norfloxacin ..

  • N-Mannich base of norfloxacin was synthesized

    Norfloxacin has a bactericidal action and it causes inhibition of bacterial DNA synthesis

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