Call us toll-free

Synthesis of 1,3,4-oxadiazoles - Organic Chemistry Portal

Categories: Synthesis of N-Heterocycles, Synthesis of O-Heterocycles > Synthesis of 1,3,4-oxadiazoles

Approximate price

Pages:

275 Words

$19,50

PDF Downloads : Oriental Journal of Chemistry

AIMST University pledges to provide the best array of services and facilities to meet the discerning needs of our students. We have a range of specialist services ready to help and support them during their time with us. Our Student Affairs Officers will assist students in making arrangements for accommodation, transportation and even help to organise extracurricular activities for them. We also have a team of professionally trained Student Counsellors who are ever willing to assist students in handling any personal difficulties or problems. Students who require financial assistance may also contact the Student Affairs Division.

Diligent Security Officers help to ensure the safety of our students while healthcare needs can be met at the Student Health Clinic. Above all these, we have a strong team of support staff to ensure efficient and up-to-date learning facilities such as computer laboratories and a fast-growing library of books, journals and other resources for information retrieval. Our International Office is a one-stop centre catering to enquiries from international students, as AIMST University opens its door to students from the region and the rest of the world. With the services and facilities provided, we hope to create a cosy home-away-from-home environment for all our students and to provide the right atmosphere so that they can experience a lively, exciting and productive university life.

Sigma-Aldrich Online Catalog Product List: C4 to C7

All melting points were determined on a Melt-Temp R apparatus equipped with a digital thermometer and are uncorrected. The IR spectra were measured as potassium bromide pellets on a Digilab Scimitar Series FT-IR Spectrophotometer; the wave numbers are given in cm-1. The 1H-NMR spectra were recorded in DMSO-d6 or CD3COCD3 solutions on Bruker ARX-300 spectrometer at ambient temperature. Chemical shifts were recorded as δ values in parts per millions (ppm) and were indirectly referenced to tetramethylsilane via residual solvent signal (2.49 for 1H). MS spectra were obtained using an instrument produced by Agilent Technologies, Wilmington, DE, USA. The instrument, Accurate Mass Q-TOF LC/MS 6520 was operated via the manufacture’s software, Mass Hunter. Samples were dissolved in acetonitrile/water mixture (95/5 v/v) to obtain a concentration of 10 μg/mL and 0.05 mL were directly injected into the electrospray source using the auto sampler at a rate of 0.05 ml/min. The instrument was operated in High resolution mode with an acquisition rate of 4 GHz. The source voltage was set at 4,000 V, the spray gas flow at 5 L/min, heating gas temperature at 325 °C and the fragmentor potential at 215 V. All chemical reagents were obtained from the Aldrich Chemical Company.

The chemistry of isatins: a review from 1975 to 1999 - …

N’’-phenylthiocarbonohydrazide: phenylhydrazine (0.1 mol) was dissolve in ethanol (95%, 50ml) and ammonia solution 20 ml then CS2 (20 ml) was added slowly within 15 min with shaking and solution allow to stand for 1 hr. to it sodium chloroacetate (0.10 mol) and 50% hydrazine hydrate (20 ml)was added. The reaction mixture was warmed gently, filtered and evaporated to half of its volume and kept overnight. The solid thus obtained was filtered and purified by recrystallization from ethanol.

2-(substituted phenyl)-5-(2-phenylhydrazinyl)-1,3,4-thiadiazole: a mixture of N’’-phenylthiocarbonohydrazide (0.10 mol), an aromatic acid and phosphorous oxychloride (25 ml) was refluxed for 18-22 hr. after cooling to RT the reaction mixture was poured into the crushed ice and kept overnight. The solid thus separated was filtered, washed with water, dried and purified by recrystallization from methanol.

The Chemistry of Isatins: a Review from 1975 to 1999

All rights reserved.A new series of thiosemicarbazones (TSCs) and their 1,3,4-thiadiazolines(TDZs) containing acetamide group have been synthesized fromthiosemicarbazide compounds by the reaction of TSCs with cyclic ketonesas well as aromatic aldehydes.

Products of Compounds containing a 1-1,2,4- triazole derivatives and many mono-, di- and tri-substituted 1,2,4-triazole-5-thiones Polyamide containing -methylimidazole (Im) can be combined in antiparallel side-by-side dimericcomplexes with the minor groove of DNA[11], also compound 2-Amino-3-(4-carboxy-1-imidazol-1-yl) propionic acid has been examined as an inhibitor of diaminopimelic acid dehydrogenase from [12]

Order now
  • 1 applied ijans synthesis of 2,5 disubstituted 1,3 ..

    Recent Literature

  • Issuu is a digital publishing platform ..

    Oriental Journal of Chemistry is a peer reviewed quarterly research journal of pure and applied chemistry

  • Synthesis of Related Compounds of Thiosemicarbazide. …

    Furans

Order now

Synthesis of Related Compounds of Thiosemicarbazide

Novel derivatives of 1,2,4,-triazole, 1,3,4-thiadiazole and 1,3,4-oxadiazole were synthesized from cyclization of new 1-[4-(phenylsulfonyl)benzoyl]-4-(4-fluorophenyl)-thiosemicarbazide 2 which was obtained by reaction of the 4-(phenylsulfonyl)-benzoic acid hydrazide 1 with 4-fluorophenyl isothiocyanate. The compound 2, in basic medium, gave 1,2,4-triazole-3(4H)-thione 3, whereas in acidic medium 1,3,4-thiadiazol-2-amine 5 was obtained. The synthesis of 1,3,4-oxadiazol-2-amine 6 was carried out by reaction of the same acylthiosemicarbazide 2 with yellow mercuric oxide. Treatment of 1,2,4-triazole 3 with ethyl bromoacetate led to the S-alkylated 1,2,4-triazole derivative 4. The newly synthesized compounds were characterized by elemental analysis and spectral studies (IR, UV-VIS, 1H-NMR, 13C-NMR, MS). All the synthesized compounds have been evaluated in vitro for their antibacterial activity against several strains of pneumococci and different type/reference strains of oral streptococci.

Preparation of halomethyl-1,3,4-thiadiazoles

Core courses related to clinical and community pharmacy services will be taught, which prepares the students to undergo the training in community, hospital and clinical pharmacy domains.

Upon completion of the university programme, graduates have to undergo provisionally registered pharmacist training for 12 months in a government hospital or institutions recognized by the Pharmacy Board of Malaysia. Subsequently, they will be attached to the government hospital/institutions for a period of 1 year for compulsory service. The graduates are required to pass the Forensic Pharmacy and Ethics Examination conducted by the Pharmacy Board of Malaysia. Subsequently, they will be attached to the government hospital/institutions for a period of 1 year for compulsory service. The graduates are required to pass the Forensic Pharmacy and Ethics Examination conducted by the Pharmacy Board of Malaysia, before they are allowed to practice as Fully Registered Pharamacists.

Order now
  • Kim

    "I have always been impressed by the quick turnaround and your thoroughness. Easily the most professional essay writing service on the web."

  • Paul

    "Your assistance and the first class service is much appreciated. My essay reads so well and without your help I'm sure I would have been marked down again on grammar and syntax."

  • Ellen

    "Thanks again for your excellent work with my assignments. No doubts you're true experts at what you do and very approachable."

  • Joyce

    "Very professional, cheap and friendly service. Thanks for writing two important essays for me, I wouldn't have written it myself because of the tight deadline."

  • Albert

    "Thanks for your cautious eye, attention to detail and overall superb service. Thanks to you, now I am confident that I can submit my term paper on time."

  • Mary

    "Thank you for the GREAT work you have done. Just wanted to tell that I'm very happy with my essay and will get back with more assignments soon."

Ready to tackle your homework?

Place an order