Questions about the relationship of proteins and nucleic acids.

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RNA is a type of nucleic acid called ribonucleic acid:

Examines the role of nucleic acids in protein synthesis.

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The role of deoxyribonucleic acid in ribonucleic acid synthesis.

To make sure you grasp the relationship between nucleic acids and proteins, take amoment to answer the following questions (which are also shown in Exercise 3 in yourworkbook). The answers are not given below. The importance of this exercise is in takingthe time to compose your answers and put them in writing. Should you need to review anymaterial, please do so. You may have your answers checked by showing them to theinstructor in the lab or by e-mailing them to your on-line instructor.

Effect of actinomycin D on cellular nucleic acid synthesis and virus production.

DNA and RNA each contain four nucleotides. Bothcontain the same purines adenine and guanine andboth also contain the pyrimidine cytosine. But the fourthnucleotide in DNA is thymine, whereas RNA uses uracil to completeits quartet of nucleotides.

nucleic acids & protein synthesis notes b1 - Biology …

The inhibition of the enzymatic synthesis of ribonucleic acid and deoxyribonucleic acid by actinomycin D and proflavin.

The amines that form nucleic acids fall into twocategories: purines and pyrimidines.There are three pyrimidines cytosine, thymine, and uracil andtwo purines adenine and guanine, asshown in the figure below.

The carbon atoms in the sugar at the center of a nucleotideare numbered from 1´ to 5´. The -OH group on the 3´ carbon ofone nucleotide can react with the phosphate attached to the 5´carbon of another to form a dinucleotide held together byphosphate ester bonds. As the chain continues to grow, it becomesa polynucleotide. A short segment of a DNA chainis shown in the figure below.

Nucleotide Metabolism: Nucleic Acid Synthesis

The Role of DNA in Protein and Enzyme Synthesis - …

For many years, the role of nucleic acids in living systemswas unknown. In 1944 Oswald Avery presented evidence that nucleicacids were involved in the storage and transfer of the geneticinformation needed for the synthesis of proteins. This suggestionwas actively opposed by many of his contemporaries, who believedthat the structure of the nucleic acids was too regular and therefore too dull to carry theinformation that codes for the thousands of different proteins acell needs to survive.

The sequence of the nucleotides in DNA can be referred to as the genetic code.Each portion of the nucleotide sequence in DNA that is responsible for the length andsequence of amino acids in one particular protein can be called a gene.Our DNA seems to be ultimately responsible for the size, shape and function of everyprotein that our bodies make. Similarly, the DNA of each plant and animal seems to beultimately responsible for the size, shape and function of every protein that each of themmakes.

Nucleic Acids and Protein Synthesis Flashcards | Quizlet
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  • What Is the Role of DNA in Protein Synthesis? (with …

    Javascript not enabled Name: Nucleic Acids Modified True/FalseIndicate whether the statement is true or false

  • The role of DNA in protein synthesis

    The amino acid metabolism page details the synthesis and breakdown of essential and non-essential amino acids.

  • DNA is stand for the deoxyribose nucleic acids

    The DNA as the primary macromolecule of heredity has been shown to play a major role in protein and enzyme synthesis

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Nucleic Acids and Protein Synthesis

The results of currently available commercial multiplex methods are available within one to six hours, depending on the pathogen under investigation. The confirmation of viral or bacterial nucleic acid does, however, not enable any conclusions regarding the pathogens’ ability to multiply or infectivity ()

The Role of Dna in Protein Synthesis Essay - 472 Words

In the setting of multiplex-PCR, sampling and transporting specimens is also of major importance. Suitable specimens to confirm respiratory pathogens can be obtained from the upper or lower respiratory tract—that is, nasopharyngeal aspirate, pharyngeal swabs, nasopharyngeal swabs, or bronchoalveolar lavage fluid. The confirmation frequency of pathogens in children with acute respiratory symptoms may be in excess of 80%. In adults it is notably lower, with only 20% in some studies (, ). One of the reasons for this may be the fact that children have much higher viral titers. Furthermore, in view of the fact that respiratory tract infections in children occur in close succession during the winter season, it can be assumed that infections actually overlap. This may provide an explanation for the fact that viral nucleic acids of different viruses in one specimen are found virtually only in children—for example, in 8% of all specimens analyzed by the authors of this article ().

The Role of DNA in Protein Synthesis DNA is found ..

The detectability of viral nucleic acids is an important contribution to the diagnostic assessment of children with severe respiratory infection. For these highly sensitive diagnostic tests to be used optimally, primary viral infections must be distinguished from bacterial superinfections.

The role of RNA in protein synthesis was suspected already in 1939

Multiplex PCR is a highly sensitive, highly specific test for the detection of viral nucleic acids in respiratory secretions. If PCR reveals the presence of RNA derived from respiratory syncytial virus, human metapneumovirus, parainfluenza virus, or influenza virus, then an acute infection caused by the corresponding pathogen is probably present, and further treatment can be given accordingly. On the other hand, the nucleic acids of adeno-, boca-, rhino- or coronaviruses can be found in relatively trivial infections as well as in asymptomatic persons, probably reflecting either a prior infection or a current subclinical one. For children in particular, upper respiratory infections are so common in the winter months that acute and prior infections with these pathogens cannot be distinguished by multiplex PCR. The use of multiplex PCR in children has not been shown to shorten hospital stays or to lessen antibiotic consumption or overall cost.

Nucleic Acid Database Images of DNA, RNA and complexes.

For a long time it was assumed that symptomatic infection with respiratory tract viruses was regularly shown by the confirmation of viral nucleic acids in respiratory secretions. However, in recent years, there have been increasing indications that this is not necessarily the case. Bocaviruses constitute an example: the clinical importance of these human parvoviruses, which were discovered in 2005, remains the subject of controversy. Bocavirus DNA can be confirmed in the respiratory tract of even asymptomatic children; a high concentration of these viruses in respiratory specimens seems to be associated with symptoms (). Only quantitative monoplex-PCR or multiplex-PCR, which is usually not available, can provide information about virus concentration.

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